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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ALPK2 All Species: 5.76
Human Site: T583 Identified Species: 15.83
UniProt: Q86TB3 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.38
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86TB3 NP_443179.3 2170 237013 T583 T Q S D K R E T S H T T A A A
Chimpanzee Pan troglodytes XP_523937 2152 234020 T583 T Q S D K R E T S H T T A A A
Rhesus Macaque Macaca mulatta XP_001089001 1927 209300 D429 A R E E F A S D N L L N M D E
Dog Lupus familis XP_541086 2143 231365 G611 T Q S D K R A G L R A K A E A
Cat Felis silvestris
Mouse Mus musculus Q91ZB0 1921 208932 S423 I Q E T I G E S S S L D Q M L
Rat Rattus norvegicus XP_574162 1448 157347
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510874 2304 253497 G729 A R S D S R D G F Q V T A N G
Chicken Gallus gallus XP_424461 1802 200116 D304 M A D S C A R D T G A A L T N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_688314 1984 219144 D486 S Q T P I M K D P M I D E P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.6 78 61.9 N.A. 51 36.4 N.A. 34.3 30 N.A. 22.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 94.4 80.9 71.9 N.A. 61 47.5 N.A. 47.8 46.3 N.A. 40.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 53.3 N.A. 20 0 N.A. 33.3 0 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 20 53.3 N.A. 26.6 0 N.A. 46.6 6.6 N.A. 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 23 12 0 0 0 23 12 0 0 0 23 12 45 23 34 % A
% Cys: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 12 45 0 0 12 34 0 0 0 23 0 12 0 % D
% Glu: 0 0 23 12 0 0 34 0 0 0 0 0 12 12 12 % E
% Phe: 0 0 0 0 12 0 0 0 12 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 12 0 23 0 12 0 0 0 0 12 % G
% His: 0 0 0 0 0 0 0 0 0 23 0 0 0 0 0 % H
% Ile: 12 0 0 0 23 0 0 0 0 0 12 0 0 0 0 % I
% Lys: 0 0 0 0 34 0 12 0 0 0 0 12 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 12 12 23 0 12 0 12 % L
% Met: 12 0 0 0 0 12 0 0 0 12 0 0 12 12 0 % M
% Asn: 0 0 0 0 0 0 0 0 12 0 0 12 0 12 12 % N
% Pro: 0 0 0 12 0 0 0 0 12 0 0 0 0 12 0 % P
% Gln: 0 56 0 0 0 0 0 0 0 12 0 0 12 0 0 % Q
% Arg: 0 23 0 0 0 45 12 0 0 12 0 0 0 0 0 % R
% Ser: 12 0 45 12 12 0 12 12 34 12 0 0 0 0 12 % S
% Thr: 34 0 12 12 0 0 0 23 12 0 23 34 0 12 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _